Oxycodone is used to relieve pain severe enough to require opioid treatment and when other pain medicines did not work well enough or cannot be tolerated. It belongs to the group of medicines called opioid analgesics (pain medicines). Oxycodone, sold under the brand names Roxicodone and OxyContin (which is the extended-release form) among others, is a semi-synthetic opioid used medically for the treatment of moderate to severe pain. Following a safety review by the MHRA and advice from the CHM, treatment of postoperative pain will be removed from the licensed indications of modified-release morphine and modified-release oxycodone due to the potential for harm and increased risk of persistent postoperative opioid use (PPOU) and opioid-induced ventilatory impairment (OIVI). Oxycodone is used to manage pain severe enough to require an opioid pain medicine when other pain medicines do not treat pain well enough, or are not tolerated. Includes oxycodone side effects, dose, reviews, warnings, and more. Oxycodone hydrochloride tablets contain oxycodone, a mu-agonist opioid of the morphine type and is a Schedule II controlled substance. Oxycodone hydrochloride tablets, like other opioids used in analgesia, can be abused and is subject to criminal diversion. The relative bioavailability of oxycodone hydrochloride compared to extended-release oxycodone is unknown, so conversion to extended-release oxycodone may lead to increased risk of excessive sedation and respiratory depression. Roxicodone (oxycodone hydrochloride) is a prescription medicine used to treat the symptoms of moderate-to-severe pain and chronic severe pain. Roxicodone may be used alone or with other medications. Oxycodone is a medicine that is used to help treat severe pain. Common side effects include constipation, nausea, vomiting, stomach pain, headache, and dizziness. Do not drive or do other. NHS information about the medicine oxycodone, including what it's used for, who can take it, how to take it and side effects. Easy-to-read patient tips for oxycodone covering how it works, benefits, risks, and best practices.